TEST BANK
ABRAMS’ CLINICAL DRUG THERAPY RATIONALES FOR NURSING
PRACTICE 13TH EDITION
GERALYN FRANDSEN
, Pre-Lecture Quiz, Chapter 1, The Foundation of Pharmacology: Quality and
Safety
True/False
1. The trade or brand name is related to the chemical or official name and isindependent
of the manufacturer.
2. The Harrison Narcotic Act prohibits fraudulent claims of drug
effectiveness.
3. Prescriptions for Schedule II drugs cannot be refilled.
4. Controlled drugs are categorized according to therapeutic usefulness andpotential
for abuse.
5. The Food and Drug Administration (FDA) is responsible for assuring that new drugs
are safe and effective before approving the drugs and allowingthem to be marketed.
Fill in the Blank
1. Individual drugs that represent groups of drugs are called .
2. Drugs are classified according to their effects on particular body systems,their
therapeutic uses, and their characteristics.
3. Drugs may be given for local or effects.
4. The goals of most pharmacoeconomic research are to identify
therapy regimens that provide the desired benefits at theleast cost.
5. Phase studies help to determine whether the potentialbenefits
for the drug outweigh the risks.
,Pre-Lecture Quiz, Chapter 2, Basic Concepts and Processes
True/False
1. Distribution is the method by which drugs are inactivated or
biotransferred by the body.
2. Toxic concentrations may stem from a single large dose or repeated smalldoses.
3. Ingesting tyramine-containing foods with MAO inhibitors may producesevere
hypertension.
4. Naloxone is used to relieve respiratory depression associated withmorphine.
5. Hyperthyroidism slows metabolism, which shortens drug action andhastens
elimination.
Fill in the Blank
1. Activated is considered the “universal” antidote.
2. is the process that occurs from the time a drug enters thebody to
the time it enters the bloodstream to be circulated.
3. Body weight affects drug action mainly in relation to .
4. During pregnancy, drugs cross the and may harm the fetus.
5. are used in clinical drug trials to compare the medicationbeing
tested with a “dummy” medication.
,Pre-Lecture Quiz, Chapter 3, Medication Administrationand the
Nursing Process of Drug Therapy
True/False
1. The fact that a physician wrote an erroneous order excuses the nursefrom legal
liability if he or she carries out that order.
2. It is safer and quicker to utilize abbreviations for drug names and routesof
administration.
3. Controlled-release tablets can be crushed or chewed for slow absorption.
4. An example of a transdermal formulation includes nitroglycerin.
5. The desired or ordered dose and the available or labeled dose must be inthe same
units of measurement.
Fill in the Blank
1. Insulin syringes are calibrated to measure up to units of
insulin.
2. The term refers to lumen size, with larger numbers
indicating smaller lumen sizes.
3. Enteric-coated tablets and capsules are coated with a substance that is
in stomach acid.
4. The most commonly used system of measurement is the
system.
5. Milliequivalents express the activity of a drug.
, Pre-Lecture Quiz, Chapter 4, Pharmacology and the Care of theInfants and
Pediatric Patients
True/False
1. Pediatric drug doses are determined strictly using the child’s weight.
2. Total body water, fat stores, and protein amounts have no effect on drugs
administered to the pediatric population.
3. In children over the age of 2, immature liver function limits the amount ofprotein
binding by drugs.
4. Injections in infants should be administered in the vastus lateralis.
5. The risk of CNS effects related to drugs is higher in infants than in adultsbecause of
the immature blood–brain barrier.
Fill in the Blank
1. may play a causal role in inducing suicide in pediatric patients.
2. By the age of , children have developed pharmacokinetic responsesthat
resemble those of adults.
3. injections are avoided in pediatric patients because of the
associated pain and unpredictable absorption.
4. Due to an immature , drugs and other chemicals may more easilyaffect
the CNS in young infants.
5. Intravenous (IV) medications should be administered using
technology.
, Pre-Lecture Quiz, Chapter 5, Pharmacology and the Care ofAdults and
Geriatric Patients
True/False
1. People less than 65 years old are the largest health care consumer group.
2. Thiazide diuretics are the most effective treatment of hypertension in olderadults.
3. Physical activity in the older adult has no effect on drug response.
4. Water-soluble drugs such as antibiotics are distributed in smaller volumes due tothe decrease
in total body fluid volume.
5. In drugs with a longer half-life, doses should be decreased.
Fill in the Blank
1. The treatment of chronic illnesses and associated comorbidities results in
.
2. In 1997, the was developed as a way to identify potentially
inappropriate medications used by the older adult.
3. Decreased circulation means that medications are slowly absorbed.
4. Age-related changes to the liver affects drug .
5. One key to increased medication adherence is the patient
regarding administration and adverse effects.
,Pre-Lecture Quiz, Chapter 6, Pharmacology and the Care ofPregnant or
Lactating Woman
True/False
1. Castor oil may be used to treat constipation in pregnant women.
2. Uterine contractions with cervical changes before 37 weeks of gestationare
considered preterm labor.
3. Nifedipine is associated with more adverse effects than magnesiumsulfate or
terbutaline.
4. Pitocin is the drug of choice for prevention of control of postpartumuterine
bleeding.
5. Women with HIV infection should not breast-feed.
Fill in the Blank
1. Drug-induced teratogenicity is most likely to occur when drugs are takenduring the
trimester of pregnancy.
2. Folic acid supplementation is especially important to prevent
birth defects.
3. The criterion for a diagnosis of gestational diabetes is a fasting plasmaglucose
level of more than mg/dL.
4. Preeclampsia is manifested by hypertension and .
5. Drug effects are less predictable due to during pregnancy.
, Pre-Lecture Quiz, Chapter 7, Pharmacology and Women’sHealth
True/False
1. Conditions involving low levels of adipose tissue, such as anorexia nervosa and
malnutrition, can contribute to amenorrhea.
2. Estradiol, estrone, and estriol are examples of exogenous hormones.
3. Common side effects of transdermal estradiol patches, such as Climara, includenausea and
vomiting.
4. Continuous-dosing oral contraceptives are helpful in treating menorrhagia.
5. Concurrent use of the anticonvulsant phenytoin can increase the effectiveness oforal
estrogens.
Fill in the Blank
1. The female sex hormones estrogen and progesterone are produced primarily in the ovaries
and secondarily by the adrenal in nonpregnant women.
2. When used in hormone replacement therapy (HRT), the purpose of progestin isto prevent
cancer.
3. The primary use of combination (estrogen–progestin) contraceptives is toprevent .
4. Cigarette smoking increases the risk for cardiovascular adverse effects in womenover age
taking oral contraceptives.
5. A black box warning accompanying medroxyprogesterone injections notes anincreased
risk for loss.
, Pre-Lecture Quiz, Chapter 8, Pharmacology and Men’sHealth
True/False
1. Acquired male hypogonadism can be caused by alkylating agents,testicular
trauma, or radiation exposure.
2. Children receiving testosterone for hormone deficiencies must haveperiodic
radiographs of the hands and wrists.
3. Natural-occurring androgens are usually administered by the oral route.
4. DHEA supplements can cause hair loss and somnolence.
5. Tamsulosin (Flomax) blocks alpha-adrenergic receptors in the bladder andprostate.
Fill in the Blank
1. Testosterone is released in response to stimulation by
hormone.
2. Androgens and anabolic steroids given to enhance athletic performanceare called
.
3. The phosphodiesterase type 5 inhibitor sildenafil is frequently used totreat
dysfunction.
4. Doxazosin (Cardura) and alfuzosin (Uroxatral) block -
adrenergic receptors.
5. Smaller doses of 5-alpha reductase inhibitors are indicated to treat
pattern baldness.
, Pre-Lecture Quiz, Chapter 9, Drug Therapy for CoagulationDisorders
True/False
1. Thrombogenesis may be lifesaving when it occurs as a response to hemorrhage.
2. Heparin is absorbed from the gastrointestinal (GI) tract.
3. Dosage of LMWHs should be reduced in clients with severe renal impairment.
4. During heparin therapy, the aPTT should be maintained at approximately 3.0times the
control or baseline value.
5. Vitamin K (Mephyton) is the antidote to aspirin.
Fill in the Blank
1. is considered a second-line drug for clients who cannot takeaspirin.
2. Thrombolytic agents stimulate conversion of plasminogen to .
3. Protamine sulfate is a(n) for standard heparin and LMWHs.
4. Heparin is the anticoagulant of choice in acute disorders.
5. dosage is regulated according to the INR.
ABRAMS’ CLINICAL DRUG THERAPY RATIONALES FOR NURSING
PRACTICE 13TH EDITION
GERALYN FRANDSEN
, Pre-Lecture Quiz, Chapter 1, The Foundation of Pharmacology: Quality and
Safety
True/False
1. The trade or brand name is related to the chemical or official name and isindependent
of the manufacturer.
2. The Harrison Narcotic Act prohibits fraudulent claims of drug
effectiveness.
3. Prescriptions for Schedule II drugs cannot be refilled.
4. Controlled drugs are categorized according to therapeutic usefulness andpotential
for abuse.
5. The Food and Drug Administration (FDA) is responsible for assuring that new drugs
are safe and effective before approving the drugs and allowingthem to be marketed.
Fill in the Blank
1. Individual drugs that represent groups of drugs are called .
2. Drugs are classified according to their effects on particular body systems,their
therapeutic uses, and their characteristics.
3. Drugs may be given for local or effects.
4. The goals of most pharmacoeconomic research are to identify
therapy regimens that provide the desired benefits at theleast cost.
5. Phase studies help to determine whether the potentialbenefits
for the drug outweigh the risks.
,Pre-Lecture Quiz, Chapter 2, Basic Concepts and Processes
True/False
1. Distribution is the method by which drugs are inactivated or
biotransferred by the body.
2. Toxic concentrations may stem from a single large dose or repeated smalldoses.
3. Ingesting tyramine-containing foods with MAO inhibitors may producesevere
hypertension.
4. Naloxone is used to relieve respiratory depression associated withmorphine.
5. Hyperthyroidism slows metabolism, which shortens drug action andhastens
elimination.
Fill in the Blank
1. Activated is considered the “universal” antidote.
2. is the process that occurs from the time a drug enters thebody to
the time it enters the bloodstream to be circulated.
3. Body weight affects drug action mainly in relation to .
4. During pregnancy, drugs cross the and may harm the fetus.
5. are used in clinical drug trials to compare the medicationbeing
tested with a “dummy” medication.
,Pre-Lecture Quiz, Chapter 3, Medication Administrationand the
Nursing Process of Drug Therapy
True/False
1. The fact that a physician wrote an erroneous order excuses the nursefrom legal
liability if he or she carries out that order.
2. It is safer and quicker to utilize abbreviations for drug names and routesof
administration.
3. Controlled-release tablets can be crushed or chewed for slow absorption.
4. An example of a transdermal formulation includes nitroglycerin.
5. The desired or ordered dose and the available or labeled dose must be inthe same
units of measurement.
Fill in the Blank
1. Insulin syringes are calibrated to measure up to units of
insulin.
2. The term refers to lumen size, with larger numbers
indicating smaller lumen sizes.
3. Enteric-coated tablets and capsules are coated with a substance that is
in stomach acid.
4. The most commonly used system of measurement is the
system.
5. Milliequivalents express the activity of a drug.
, Pre-Lecture Quiz, Chapter 4, Pharmacology and the Care of theInfants and
Pediatric Patients
True/False
1. Pediatric drug doses are determined strictly using the child’s weight.
2. Total body water, fat stores, and protein amounts have no effect on drugs
administered to the pediatric population.
3. In children over the age of 2, immature liver function limits the amount ofprotein
binding by drugs.
4. Injections in infants should be administered in the vastus lateralis.
5. The risk of CNS effects related to drugs is higher in infants than in adultsbecause of
the immature blood–brain barrier.
Fill in the Blank
1. may play a causal role in inducing suicide in pediatric patients.
2. By the age of , children have developed pharmacokinetic responsesthat
resemble those of adults.
3. injections are avoided in pediatric patients because of the
associated pain and unpredictable absorption.
4. Due to an immature , drugs and other chemicals may more easilyaffect
the CNS in young infants.
5. Intravenous (IV) medications should be administered using
technology.
, Pre-Lecture Quiz, Chapter 5, Pharmacology and the Care ofAdults and
Geriatric Patients
True/False
1. People less than 65 years old are the largest health care consumer group.
2. Thiazide diuretics are the most effective treatment of hypertension in olderadults.
3. Physical activity in the older adult has no effect on drug response.
4. Water-soluble drugs such as antibiotics are distributed in smaller volumes due tothe decrease
in total body fluid volume.
5. In drugs with a longer half-life, doses should be decreased.
Fill in the Blank
1. The treatment of chronic illnesses and associated comorbidities results in
.
2. In 1997, the was developed as a way to identify potentially
inappropriate medications used by the older adult.
3. Decreased circulation means that medications are slowly absorbed.
4. Age-related changes to the liver affects drug .
5. One key to increased medication adherence is the patient
regarding administration and adverse effects.
,Pre-Lecture Quiz, Chapter 6, Pharmacology and the Care ofPregnant or
Lactating Woman
True/False
1. Castor oil may be used to treat constipation in pregnant women.
2. Uterine contractions with cervical changes before 37 weeks of gestationare
considered preterm labor.
3. Nifedipine is associated with more adverse effects than magnesiumsulfate or
terbutaline.
4. Pitocin is the drug of choice for prevention of control of postpartumuterine
bleeding.
5. Women with HIV infection should not breast-feed.
Fill in the Blank
1. Drug-induced teratogenicity is most likely to occur when drugs are takenduring the
trimester of pregnancy.
2. Folic acid supplementation is especially important to prevent
birth defects.
3. The criterion for a diagnosis of gestational diabetes is a fasting plasmaglucose
level of more than mg/dL.
4. Preeclampsia is manifested by hypertension and .
5. Drug effects are less predictable due to during pregnancy.
, Pre-Lecture Quiz, Chapter 7, Pharmacology and Women’sHealth
True/False
1. Conditions involving low levels of adipose tissue, such as anorexia nervosa and
malnutrition, can contribute to amenorrhea.
2. Estradiol, estrone, and estriol are examples of exogenous hormones.
3. Common side effects of transdermal estradiol patches, such as Climara, includenausea and
vomiting.
4. Continuous-dosing oral contraceptives are helpful in treating menorrhagia.
5. Concurrent use of the anticonvulsant phenytoin can increase the effectiveness oforal
estrogens.
Fill in the Blank
1. The female sex hormones estrogen and progesterone are produced primarily in the ovaries
and secondarily by the adrenal in nonpregnant women.
2. When used in hormone replacement therapy (HRT), the purpose of progestin isto prevent
cancer.
3. The primary use of combination (estrogen–progestin) contraceptives is toprevent .
4. Cigarette smoking increases the risk for cardiovascular adverse effects in womenover age
taking oral contraceptives.
5. A black box warning accompanying medroxyprogesterone injections notes anincreased
risk for loss.
, Pre-Lecture Quiz, Chapter 8, Pharmacology and Men’sHealth
True/False
1. Acquired male hypogonadism can be caused by alkylating agents,testicular
trauma, or radiation exposure.
2. Children receiving testosterone for hormone deficiencies must haveperiodic
radiographs of the hands and wrists.
3. Natural-occurring androgens are usually administered by the oral route.
4. DHEA supplements can cause hair loss and somnolence.
5. Tamsulosin (Flomax) blocks alpha-adrenergic receptors in the bladder andprostate.
Fill in the Blank
1. Testosterone is released in response to stimulation by
hormone.
2. Androgens and anabolic steroids given to enhance athletic performanceare called
.
3. The phosphodiesterase type 5 inhibitor sildenafil is frequently used totreat
dysfunction.
4. Doxazosin (Cardura) and alfuzosin (Uroxatral) block -
adrenergic receptors.
5. Smaller doses of 5-alpha reductase inhibitors are indicated to treat
pattern baldness.
, Pre-Lecture Quiz, Chapter 9, Drug Therapy for CoagulationDisorders
True/False
1. Thrombogenesis may be lifesaving when it occurs as a response to hemorrhage.
2. Heparin is absorbed from the gastrointestinal (GI) tract.
3. Dosage of LMWHs should be reduced in clients with severe renal impairment.
4. During heparin therapy, the aPTT should be maintained at approximately 3.0times the
control or baseline value.
5. Vitamin K (Mephyton) is the antidote to aspirin.
Fill in the Blank
1. is considered a second-line drug for clients who cannot takeaspirin.
2. Thrombolytic agents stimulate conversion of plasminogen to .
3. Protamine sulfate is a(n) for standard heparin and LMWHs.
4. Heparin is the anticoagulant of choice in acute disorders.
5. dosage is regulated according to the INR.
