Week 5 Concepts: Nutrition
Acid-Controlling Drugs
Prepare: Acid-Controlling Drugs
Stomach Areas
Identify the areas of the stomach.
Gastric Glands
Match the gastric gland cell with its function.
Produce and secrete hydrochloric acid Parietal cells
Secrete pepsinogen which is a precursor to pepsin Chief cells
Provide a protective coating for the stomach Mucosa cells
Parietal Cells
Which receptors in the stomach are responsible for stimulating the secretion of acid from the parietal cells? Selec
all that apply.
Histamine
Adenosine triphosphate (ATP) pump
Proton ion
Gastrin
Acetylcholine (ACh)
Self-Check: Stomach Acid
Gastric Hyperacidity
Gastric hyperacidity is the over production of stomach acid.
Stomach Acid
The pH of stomach acid is 1-4.
Self-Check: Hyperacidity
Gastroesophageal Reflux Disease (GERD)
Gastroesophageal reflux disease is when excessive acid backs up into the esophagus.
Acid-controlling Drugs
Match the acid-controlling drugs with how they work.
Antacids Reduce acid by neutralization within the stomach
Histamine (H) 2 Blockers (H2 receptor agonist) Reduce acid by blocking signals to the parietal cells
,Proton Pump Inhibitors Reduce acid by working within the parietal cells
Self-Check: H. Pylori (Helicobacter pylori)
Helicobacter pylori (H. pylori)
Helicobacter pylori (H. pylori) is a Bacteria that can infect the gastric track.
Reflect: Acid-Controlling Drugs
Acid-controlling Drugs
The telehealth nurse is responding to question send to the Hancock Healthcare Services’ social media page. Revie
the questions and choose the best response.
Question
Mandy345 asks:
I have heartburn and I am in the pharmacy. Do all acid controlling drugs work the same way?
Choose your best response from the choices given below.
“Acid controlling drugs do not all work the same way.”
“It depends on each person’s genetics.”
“Yes, they do.”
“I think so.”
Question
MrTom2u wrote:
I take a lot of prescribed daily medication, including digoxin. Is it safe to take any type of acid controlling drugs wi
my medications?
Choose your best response from the choices given below.
“Yes, acid controlling drugs are safe. You may also need to take an extra dose of your digoxin to stay in your
therapeutic range.”
“Yes, acid controlling drugs are safe and should be taken with your nightly medications.“
“Yes, acid controlling drugs are safe and can be taken with your daily medications.”
“Yes, acid controlling drugs are generally safe. Check with your doctor for the best choice of acid controlling drugs fo
you.”
Question
Mavis52 wrote:
What lifestyle changes can I start that will prevent/reduce my heartburn (hyperacidity) symptoms?
Choose the correct response from the choices given below.
“Chewing gum will prevent your hyperacidity symptoms.”
“Eat later in the evening so your stomach can digest your food while you sleep.”
“Drinking more water will prevent your hyperacidity symptoms.”
“Changing your diet and reducing stress can decease your symptoms.”
Question
Mavis52 wrote back:
My husband said that smelling his food on the grill will make my stomach secrete digestive fluid. Is this true?
Choose the correct response from the choices given below.
“No, food must be present in the stomach for the secretion of digestive enzymes.”
“Yes. Smelling, seeing, or tasting food can cause your stomach to secrete digestive acids.”
“Yes, but it only happens with smelling grilled food.”
“No, only chewing and swallowing food makes you secrete stomach acids.”
Question
Mav12 asks:
Do these work the same way to reduce acid in my stomach?
Acid-reducing medication
,Effervescent tablet antacid
Choose your best response from the choices given below.
“Yes, they both neutralize the acid present in the stomach.”
“Yes, they work the same in your stomach; they just have different names.”
“No, the effervescent tablet antacid neutralizes the acid in the stomach and the acid-reducing medication blocks
signals to cells in your stomach.”
“No, the acid-reducing medication neutralizes the acid in the stomach and the effervescent tablet antacid blocks
signals to cells in your stomach.”
Question
You just received a direct message (DM) from Twitter. Mary10 wrote:
@HHSH My Dad was just admitted to the intensive care unit. Why was he given an acid-controlling drug? He is
intubated and not eating.
Choose the best response from the choices given below.
“Sorry to hear about your dad. This is old school care and is outdated and not needed.”
“Sorry to hear about your dad. This is not a normal course of treatment.”
“Sorry to hear about your dad. It was most likely given to prevent stress related ulcers.”
“Sorry to hear about your dad. It was most likely given to shrink his stomach.”
Parietal Cells
The secondary response of parietal cells activates the hydrogen–potassium–adenosine triphosphatase (ATP) pump.
Antacids (magnesium carbonate, aluminum hydroxide, calcium
carbonate, sodium bicarbonate)
Prepare: Antacids
Antacid
Which salt compounds are contained in antacid? (Select all that apply.)
Manganese
Sodium
Chloride
Magnesium
Aluminum
Calcium
Simethicone
What is the purpose of simethicone?
Reduce gas
Dilate stomach vessels
Reduce gastric motility
Promote defecation
Side Effect of Antacids
Antacids are made of salt compounds. Magnesium antacid salt compound can cause the side effect of diarrhea.
Self-Check: Antacids
Therapeutic Effects of Antacids
What are the expected therapeutic effects of antacids? Select all that apply.
Raise stomach pH
Lower stomach pH
Allow ulcers time to heal
Neutralize stomach acids
, Provide relief from heartburn
Treat patients with heart disease
Self-Check: Drug Interactions
Match the interaction with the definitions.
Reduces the ability of the other drug to be absorbed into the body Adsorption
Chemical inactivation of other drugs that produces insoluble complexes Chelation
Increases the absorption of basic drugs and decreases the absorption of acidic Increased stomach pH
drugs
Increases the excretion of acidic drugs and decreases the excretion of basic drug Increased urinary pH
Self-Check: Antacid Compounds
Combining two salt compounds in an antacid has what beneficial effect?
Increase absorption of the antacid
Decrease the antacid efficacy
Prevent side effects from each salt compounds.
Prevent metabolic acidosis
Antacid Side Effects
Drag the correct side effect for each of the antacid salt compounds given below:
Salt Compound Side effects
Magnesium-Containing Antacids Carbonate salt Diarrhea
Aluminum-Containing Antacids Carbonate salt Constipation
Calcium-Containing Antacids Carbonate salt Constipation/Diarrhea
Sodium-Containing Antacids Bicarbonate salt Flatulence, gastric distention
Reflect: Antacids
Side Effects
A client takes an aluminum-containing antacid, such as aluminum hydroxide, for which side effect?
Diarrhea
Fluid retention
Constipation
Gastrointestinal (GI) upset
Antacid Drug
Mike has chronic renal failure. Magnesium-containing antacids may not be the best based on the patient's medical conditio
Antacid Table
Complete the table below by dragging the appropriate choices into the blank cells.
Acid-Controlling Drugs
Prepare: Acid-Controlling Drugs
Stomach Areas
Identify the areas of the stomach.
Gastric Glands
Match the gastric gland cell with its function.
Produce and secrete hydrochloric acid Parietal cells
Secrete pepsinogen which is a precursor to pepsin Chief cells
Provide a protective coating for the stomach Mucosa cells
Parietal Cells
Which receptors in the stomach are responsible for stimulating the secretion of acid from the parietal cells? Selec
all that apply.
Histamine
Adenosine triphosphate (ATP) pump
Proton ion
Gastrin
Acetylcholine (ACh)
Self-Check: Stomach Acid
Gastric Hyperacidity
Gastric hyperacidity is the over production of stomach acid.
Stomach Acid
The pH of stomach acid is 1-4.
Self-Check: Hyperacidity
Gastroesophageal Reflux Disease (GERD)
Gastroesophageal reflux disease is when excessive acid backs up into the esophagus.
Acid-controlling Drugs
Match the acid-controlling drugs with how they work.
Antacids Reduce acid by neutralization within the stomach
Histamine (H) 2 Blockers (H2 receptor agonist) Reduce acid by blocking signals to the parietal cells
,Proton Pump Inhibitors Reduce acid by working within the parietal cells
Self-Check: H. Pylori (Helicobacter pylori)
Helicobacter pylori (H. pylori)
Helicobacter pylori (H. pylori) is a Bacteria that can infect the gastric track.
Reflect: Acid-Controlling Drugs
Acid-controlling Drugs
The telehealth nurse is responding to question send to the Hancock Healthcare Services’ social media page. Revie
the questions and choose the best response.
Question
Mandy345 asks:
I have heartburn and I am in the pharmacy. Do all acid controlling drugs work the same way?
Choose your best response from the choices given below.
“Acid controlling drugs do not all work the same way.”
“It depends on each person’s genetics.”
“Yes, they do.”
“I think so.”
Question
MrTom2u wrote:
I take a lot of prescribed daily medication, including digoxin. Is it safe to take any type of acid controlling drugs wi
my medications?
Choose your best response from the choices given below.
“Yes, acid controlling drugs are safe. You may also need to take an extra dose of your digoxin to stay in your
therapeutic range.”
“Yes, acid controlling drugs are safe and should be taken with your nightly medications.“
“Yes, acid controlling drugs are safe and can be taken with your daily medications.”
“Yes, acid controlling drugs are generally safe. Check with your doctor for the best choice of acid controlling drugs fo
you.”
Question
Mavis52 wrote:
What lifestyle changes can I start that will prevent/reduce my heartburn (hyperacidity) symptoms?
Choose the correct response from the choices given below.
“Chewing gum will prevent your hyperacidity symptoms.”
“Eat later in the evening so your stomach can digest your food while you sleep.”
“Drinking more water will prevent your hyperacidity symptoms.”
“Changing your diet and reducing stress can decease your symptoms.”
Question
Mavis52 wrote back:
My husband said that smelling his food on the grill will make my stomach secrete digestive fluid. Is this true?
Choose the correct response from the choices given below.
“No, food must be present in the stomach for the secretion of digestive enzymes.”
“Yes. Smelling, seeing, or tasting food can cause your stomach to secrete digestive acids.”
“Yes, but it only happens with smelling grilled food.”
“No, only chewing and swallowing food makes you secrete stomach acids.”
Question
Mav12 asks:
Do these work the same way to reduce acid in my stomach?
Acid-reducing medication
,Effervescent tablet antacid
Choose your best response from the choices given below.
“Yes, they both neutralize the acid present in the stomach.”
“Yes, they work the same in your stomach; they just have different names.”
“No, the effervescent tablet antacid neutralizes the acid in the stomach and the acid-reducing medication blocks
signals to cells in your stomach.”
“No, the acid-reducing medication neutralizes the acid in the stomach and the effervescent tablet antacid blocks
signals to cells in your stomach.”
Question
You just received a direct message (DM) from Twitter. Mary10 wrote:
@HHSH My Dad was just admitted to the intensive care unit. Why was he given an acid-controlling drug? He is
intubated and not eating.
Choose the best response from the choices given below.
“Sorry to hear about your dad. This is old school care and is outdated and not needed.”
“Sorry to hear about your dad. This is not a normal course of treatment.”
“Sorry to hear about your dad. It was most likely given to prevent stress related ulcers.”
“Sorry to hear about your dad. It was most likely given to shrink his stomach.”
Parietal Cells
The secondary response of parietal cells activates the hydrogen–potassium–adenosine triphosphatase (ATP) pump.
Antacids (magnesium carbonate, aluminum hydroxide, calcium
carbonate, sodium bicarbonate)
Prepare: Antacids
Antacid
Which salt compounds are contained in antacid? (Select all that apply.)
Manganese
Sodium
Chloride
Magnesium
Aluminum
Calcium
Simethicone
What is the purpose of simethicone?
Reduce gas
Dilate stomach vessels
Reduce gastric motility
Promote defecation
Side Effect of Antacids
Antacids are made of salt compounds. Magnesium antacid salt compound can cause the side effect of diarrhea.
Self-Check: Antacids
Therapeutic Effects of Antacids
What are the expected therapeutic effects of antacids? Select all that apply.
Raise stomach pH
Lower stomach pH
Allow ulcers time to heal
Neutralize stomach acids
, Provide relief from heartburn
Treat patients with heart disease
Self-Check: Drug Interactions
Match the interaction with the definitions.
Reduces the ability of the other drug to be absorbed into the body Adsorption
Chemical inactivation of other drugs that produces insoluble complexes Chelation
Increases the absorption of basic drugs and decreases the absorption of acidic Increased stomach pH
drugs
Increases the excretion of acidic drugs and decreases the excretion of basic drug Increased urinary pH
Self-Check: Antacid Compounds
Combining two salt compounds in an antacid has what beneficial effect?
Increase absorption of the antacid
Decrease the antacid efficacy
Prevent side effects from each salt compounds.
Prevent metabolic acidosis
Antacid Side Effects
Drag the correct side effect for each of the antacid salt compounds given below:
Salt Compound Side effects
Magnesium-Containing Antacids Carbonate salt Diarrhea
Aluminum-Containing Antacids Carbonate salt Constipation
Calcium-Containing Antacids Carbonate salt Constipation/Diarrhea
Sodium-Containing Antacids Bicarbonate salt Flatulence, gastric distention
Reflect: Antacids
Side Effects
A client takes an aluminum-containing antacid, such as aluminum hydroxide, for which side effect?
Diarrhea
Fluid retention
Constipation
Gastrointestinal (GI) upset
Antacid Drug
Mike has chronic renal failure. Magnesium-containing antacids may not be the best based on the patient's medical conditio
Antacid Table
Complete the table below by dragging the appropriate choices into the blank cells.
