Midterm Exam: NR566/ NR 566 Advanced Pharmacology Care of the Family Exam | Questions and Verified Answers (2023/ 2024 Update)- Chamberlain

Midterm Exam: NR566/ NR 566 Advanced Pharmacology Care of the Family Exam | Questions and Verified Answers (2023/ 2024 Update)- Chamberlain 1. Aminoglycosides patient education (ex. gentamicin, tobramycin, amikacin) ~ Answer: use is associated with ototoxicity and nephrotoxicity 2. Prescribing sulfonamides during pregnancy ~ Answer: not safe (especially in first trimester)- causes birth defects ~ if taken near term, infant can develop kernicterus (brain damage caused by too much bilirubin) 3. Which cephalosporins may induce a disulfiram-like reaction if alcohol is ingested? ~ Answer: Cefazolin and cefotetan 4. sulfonamides patient education ~ Answer: complete full course even if symptoms resolved ~ take with 8-10 glasses of water or noncaffeinated beverages per day to decrease risk of crystalluria ~ protect skin from sun ~ no tanning beds ~ monitor for hypersensitivity symptoms 5. sulfonamides renal dosing ~ Answer: Avoid in older adults for ~ For patients with creatinine clearance <30mL/min: ~ For patients concurrently prescribed warfarin, avoid trimethoprim/sulfamethoxazole, macrolides, and ciprofloxacin ~ do not give if creatine is under 15 6. Gentamicin (aminoglycoside) ~ Answer: monitor Cr cl in elderly ~ renal adjustments ~ If renal dx dose reduces or dosing interval increased 7. What do we need to be aware of in our female patients of childbearing age with clindamycin ~ Answer: decrease oral contraceptive activity 8. Aminoglycosides are safe for what age group ~ Answer: children (infant <8 days old) 9. Clindamycin can be used as an alternative to what ~ Answer: penicillin 10. Specific drug to treat aspergillosis ~ Answer: Voriconazole 11. Which ones carry risk for hypotension with patients on antihypertensives? ~ Answer: Ivermectin and Moxidectin 12. Which ones can cause bone marrow suppression and liver impairment? ~ Answer: Albendazole and Mebendazole 13. Which is generally safe to give without obtaining baseline data? ~ Answer: Pyrantel Pamoate 14. How to treat tinea capitis aka ringworm ~ Answer: Drug Class - Oral antifungal (not topical) ~ Oral griseofulvin taken for 6-8 weeks, is considered standard therapy