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Summary Biostatistics Notes Tutorials

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Tutorial Notes for the Biostatistics course.

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Uploaded on
January 15, 2023
Number of pages
5
Written in
2021/2022
Type
Summary

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Review day I

mean
· mean

median
population -> .g, N
·
·


L
mode
stand.
·

·
Sample -> X,S, n
↑ dev ·
variance
types 1)
x
Data colours
ranR 2
-
·

& < 2

-Qualitative nominal ordinal measurement -> population -> 0
ata seconds
- Quantitative interval, ratio, censored ->
sample -
2 E(X- x)2


yearstime estimated
=


-




Rounding s
nnx
· -
with
↓ -


n10 -> +1 decimal




population =mean


o standard
=

deviation

sample:X mean
=




standard
s= deviation

mode= frequentvalue
most

median middle value

meanor
all
figures
#Figures


Review days
Distributions discrete
Probability - >
calculations
·

Uniform -> Proutcomes
equal
O= Pr(A) 1
-T 2(pixxi) 1
·
=
=

=


· Addition rule




-promauzenom-comexe,
geinzinganiseasesseen
-> PrCAUB) PrCA) + Pr(B)-PrCANB)
=




independentevents productsee
·
conditional

-> PrCAIB) PCA ePr(x) =




xe
-
M




Review day 3

nina
distribution
one-sided.2A
sided:

-!
2B S= standard deviation
·
(X - N(7,64))
xz
S x2
h.
2- score
-
=




#,.0",*,
·




42
M
=




·
standard error (se) Se standard error
=




<
stanct.dev.
Ep
secFl-noone
o

re
same
=




xlim p =(z
=
* O)
A use 2 -
score to find
P vice versa
samples
two different


Review
day u
·
Decision error

shypothesis No rejected when true
testing -> type I (2)
·
No includes
-
=<p> a -> type 1 (B) No rejected
not when false
↑ we ↓
t his
test always not
rejected




andopenote
·Morescearora
MA CLAIM

·
z
Mo M
=

=
one
·
sample size (n)
&> one-sided en (78)"
=
(zc zB/2 +




-> two-sided n (z) (z(x
= =

z p)2
+




C =

always probability this means i s two
it sided

, Review days Chisquared -

R
Paired
data
↓ alles is gely
Parametric t-test
↓normal distribution
·
of fit
-
goodness -

-> H0: A 0, =
MA.A =0
·
Hodata follows distribution (ex uniform distribution) If it's not
follow distribution
MA doesn't Chi square d
-
-> T
pdF
=
n
= -
1


normally distributed
·
X=E Ej(2 dF k 1
No Watje wilte n ·.
non-parametric Wilcoxin matched pair
Ej
= -




↳ noclasses verwaent
yn1)zz ntl. 1)
+




-(
=




normal distribution
&resample ofi t

verwaching
HA:

·
Parametricit-testtable 3] data
Impaired
F testFollowed by Z-testCT-test
zT
MdF parametric
·
=




Tctdf,0/ztp>d

EF-teapt.No.Inosyargiance.soit
n
=
-
1 -


obtained
->
Mx
=




Itdf;0-confidence
interval
sits an
& less reliable than t-test -



p>0.05 n 12 2
spooled
+ -




·
non-parametric Wilcoxon rankorder table 5)
-> Ttest:MO:MI -


/2 0
=


HA:M1-M2
Find A rank (find 0
-
range ofTCA
/ITC) M1 12
=




Mi M2


x
aT ↓
normal distribution
El-CM
=

parametric
-
There is a
the
significant

n
i
= difference between
two variables




Review day 6 if
yOU Tukey
· Kramer (a)
I have 3 or

Oeway anougparametric (3) more data
frequencies) 2q
1.5x
- nb)
=
(no



silicon
on
·
Ho.
M1 M2 n# samplesper group Jruskal Wallis
Non parametric=
=




M3
=




HA:atleast1 => Ntotal sample size ·
Confidence
-> rank data, sumbank
mean rank

sign diff between individuals =34.3 12 intervals nicRiR V
-1

E(X)
MT -H
=

· =
=
=




-> Scheffe
M. -Mz M1 MIN
TRANSAS dEKH Mable
= -




· SStotal ES(XY) =


2 Mono
N(MA) v
-
dfbetw =k-1
nz reject
SS between ENT. Mi
Tukey-Kramer
=


-
NMP dewithin N-K
->



sres=mswithin
=




reChitns
So within [x EniMis
=

-

X
within Sres = mi-mo xi -xjIq =
->


ANOVA:




Freeposception
Source -> HSD
aantal data
F-table
HSD(ni,nj) qX (hi
h) ↓




paramarorausp
=
+




dF N =
-
k
within 4

ay* 2n z
=




= nantal
samples
chospitals)


Review day 7
mcnemor's (2 matched
group
·



continuity correction (n > 15)
groups with freq
-> sample divided into a a, b, and

of effects/side effects - only outcomes
·
Binomial coccurence ab
sp,
atc
en e
=




x
=

n
-> sample - Zc
c]
=




-zc =

cjCI.M1 -
M2 pi
=
-
P2 = (z +


22/2.

-> (+ x p = = [z zcz p +
·
Outliers
suspected
-




-
Grubbs: I value


youcalanar
set


-> Z independent
6
=1pect- ↑
to not rejected
-> HoT -Me 0 (no -> Dixon's
difference) suspected value
=




samples 71 22
=




QQlimeMonot
HA:M1-M2 0 from
low-high index
-> sort
values
M #72 (difference
rejected
=n-
X x
-a
et Q An
Xn 2




-zaousci-iclEcti
e
-

=




xn -
X3
n0 12
= -



n 13
=


when there
are 2 samples -> Box Approach multiple suspected values
Plot

- (... - Mr pi
=
-
P2 I[z(n+nz)

if
they
+


22/2 pP+
Ptype) -> interquartile
range (IQR) =G3Q,
say more than #
·
Poisson ↓ ifthey sayless than o z-table, 0.05 -> lower limit (x) = Q- , QR upper limit(lu)
IGR

MisamplenzcTxNtoTME**I+ZRCRS
QS +
=




values outside
MA* range between likluare outliers
1x. -
X2) -
1
32
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