Tissue Engineering - introduction, risks, ethics

1.
TieeuE ENGINEEAING
Defniim : An
interdeciplory field
d hat applies ne Priniples of endineerios and

ife siences towards the development Obiolodical ubethues that
esfore maintaln, or mprove hsvejun chon r a whole ordan.
CLanger and Vacanti)
Elemente of tiesue engineering :
i isolafes cells or cell
itissue indvand subshtufes
id) cll subefanes
placed on within matrices C
or
sca folds)
Risk Assessment Factore
defvee of
invesiveness - implantatione,
Ci) intended bioachive Substances
TUdon of
enneered tissue mainly with essential
) risk during cady tUnchions
practi cing the mcthod
iv) alternative methods infectin, toxicihy e
-




Vunexpected risks -
atter all carejul & reasonable evaluatim
Intormatlon onsent
i. Disdosure
Usually contains tollcw
follewing cemente
ing clemenis i-


i. Underestünding . Capact
V. Con sent
iit. Volontarigess

Doethical Isaues:-
dene therapy animal
Experiment| treatment wth out consens embroyolsial cesearch;
res earch tra
bioenhane ments Caesthetics and oEplantahon and Xenotrans
dopind) plantation
Desigiom on human embroyo
source
ethically
Cemplche ban on
emtonic cells Allow use under certain conditons
Jor RD Uncesthdcte use
at imc g embryo development
Conditions of access o
calender deadline of enmbreyo
generation of stem cell line