NURS-6630N-5/NURS-6630C-5/NURS-6630F-5/DNRS- 6630F-5- Approaches to Treatment. Final Exam - Week 11. Questions with Verified Answers. Graded A.

Question 48 Disulfiram has been proven effective in the treatment of alcoholism, but recentlyit has been trialed in the management of cocaine addiction. What is the mechanism of action that likely helps produce these aversive effects? A. Inhibition on dopamine beta-hydroxylase B. Inhibition on aldehyde dehydrogenase C. Inhibition on alcohol dehydrogenase D. Inhibition on aldehyde reductase Response Feedback: “These reactions are thought to be mediated by the inhibitory effect of disulfiram on dopamine beta-hydroxylase. This action will elevate depleted plasma dopamine levels in chronic users and will produce abnormally high dopamine levels if cocaine is ingested; this results in a dysphoric experience in most users.” Question 49 SSRIs can be used in alcohol use disorder and offer modest drinking reduction through an anti-craving effect. A. True B. Fals e Response Feedback: “SSRIs have produced only modest drinking reductions—independent of the antidepressant effects—through an anti-craving effect” Question 50 Which of the following drugs in the treatment of Alzheimer’s Disease helps normalize glutamate by antagonizing the NMDA receptor? A. Memantine