Chapter 1 A Case for Evolutionary Thinking: Understanding HIV
1) In which of the following regions has AIDS killed the largest number of individuals?
A) India
B) Sub-Saharan Africa
C) United States
D) China
E) United Kingdom
Answer: B
Section: 1.1
Skill: Knowledge/Comprehension
2) The HIV virus contains all of the following components except ________.
A) integrase
B) double-stranded RNA
C) single-stranded RNA
D) reverse transcriptase
E) protease
Answer: B
Section: 1.1
Skill: Knowledge/Comprehension
3) The acronym HIV stands for which of the following?
A) human intercellular virus
,B) human immune virus
C) human immunodeficiency virus
D) human immunity virus
E) human immunodeficiency vector
Answer: C
Section: 1.1
Skill: Knowledge/Comprehension
4) Which of the following enzymes is responsible for transcribing viral RNA into DNA?
A) RNA polymerase
B) reverse transcriptase
C) DNA polymerase
D) reverse integrase
E) RNA duplicase
Answer: B
Section: 1.1
Skill: Knowledge/Comprehension
,5) The proteins that enable the HIV virus to bind to cells are typically CD4 and CCR5.
On what type of cells are these proteins typically observed?
A) plasma cells
B) dendritic cells
C) effector helper T cells
D) memory helper T cells
E) both C and D
Answer: E
Section: 1.1
Skill: Knowledge/Comprehension
6) The AIDS phase of HIV infection begins when the concentration of CD4 T cells in the
blood drops below what concentration?
A) 2,000 cells per cubic millimeter
B) 1,000 cells per cubic millimeter
C) 500 cells per cubic millimeter
D) 200 cells per cubic millimeter
E) No CD4 T cells are observed.
Answer: D
Section: 1.1
Skill: Knowledge/Comprehension
7) Which of the following drug categories are used to treat HIV infections?
A) integrase inhibitors
B) protease inhibitors
C) reverse transcriptase inhibitors
, D) DNAse inhibitors
E) fusion inhibitors
Answer: D
Section: 1.2
Skill: Knowledge/Comprehension
8) Coreceptor inhibitors block HIV infection by preventing which of the following?
A) binding of the HIV virion onto the plasma membrane
B) binding of the HIV virion onto the CCR5 receptor
C) binding of the HIV virion onto the gp120 protein
D) degrading the coreceptor so the virion cannot attach
E) binding of the HIV virion onto the CD4 receptor
Answer: B
Section: 1.2
Skill: Application/Analysis