PHARM 1141 EXAM 2 QUESTIONS AND CORRECT
ANSWERS (VERIFIED ANSWERS) PLUS RATIONALES
Q & A 2026|INSTANT DOWNLOAD PDF
1. Which of the following are common routes of drug
administration?
a. Oral
b. Intravenous
c. Inhalation
d. Telepathic
Rationale: Drugs can be delivered through several routes
depending on absorption, onset, and patient needs. Correct: a,
b, c
2. The process by which a drug moves from the site of
administration into the bloodstream is called:
a. Metabolism
b. Excretion
c. Absorption
d. Distribution
Rationale: Absorption is the movement of a drug into systemic
circulation. Correct: c
,3. First-pass effect primarily affects drugs administered via:
a. Oral
b. Intravenous
c. Subcutaneous
d. Intramuscular
Rationale: Oral drugs pass through the liver before systemic
circulation, which can reduce bioavailability. Correct: a
4. Which organs are primarily responsible for drug
metabolism?
a. Liver
b. Kidney
c. Lungs
d. Skin
Rationale: The liver metabolizes drugs to more water-soluble
forms for excretion. Correct: a
5. Which factors affect drug absorption?
a. Blood flow to the area
b. Drug solubility
c. Food in the stomach
d. Drug color
Rationale: Absorption depends on blood flow, solubility, and
the presence of food; drug color is irrelevant. Correct: a, b, c
,6. The time required for a drug’s plasma concentration to
decrease by half is called:
a. Peak time
b. Half-life
c. Bioavailability
d. Onset of action
Rationale: Half-life indicates how long it takes for drug
concentration to reduce by 50%. Correct: b
7. Which of the following are types of drug interactions?
a. Synergistic
b. Antagonistic
c. Additive
d. Reflexive
Rationale: Drugs can interact in ways that enhance, oppose, or
add to each other’s effects. Correct: a, b, c
8. Which of the following are signs of an allergic reaction to a
drug?
a. Rash
b. Fever
c. Anaphylaxis
d. Nausea
Rationale: Allergic reactions include skin rash, hives, and
potentially life-threatening anaphylaxis. Correct: a, c
, 9. The most accurate method of measuring a patient’s kidney
function for drug dosing is:
a. Urinalysis
b. Creatinine clearance
c. Blood pressure
d. Heart rate
Rationale: Creatinine clearance reflects kidney function and
guides dose adjustments. Correct: b
10. Which drugs require monitoring of serum levels to prevent
toxicity?
a. Digoxin
b. Gentamicin
c. Penicillin
d. Lithium
Rationale: Drugs with narrow therapeutic ranges need
monitoring to avoid toxicity. Correct: a, b, d
11. Which are considered high-alert medications?
a. Insulin
b. Heparin
c. Acetaminophen
d. Warfarin
ANSWERS (VERIFIED ANSWERS) PLUS RATIONALES
Q & A 2026|INSTANT DOWNLOAD PDF
1. Which of the following are common routes of drug
administration?
a. Oral
b. Intravenous
c. Inhalation
d. Telepathic
Rationale: Drugs can be delivered through several routes
depending on absorption, onset, and patient needs. Correct: a,
b, c
2. The process by which a drug moves from the site of
administration into the bloodstream is called:
a. Metabolism
b. Excretion
c. Absorption
d. Distribution
Rationale: Absorption is the movement of a drug into systemic
circulation. Correct: c
,3. First-pass effect primarily affects drugs administered via:
a. Oral
b. Intravenous
c. Subcutaneous
d. Intramuscular
Rationale: Oral drugs pass through the liver before systemic
circulation, which can reduce bioavailability. Correct: a
4. Which organs are primarily responsible for drug
metabolism?
a. Liver
b. Kidney
c. Lungs
d. Skin
Rationale: The liver metabolizes drugs to more water-soluble
forms for excretion. Correct: a
5. Which factors affect drug absorption?
a. Blood flow to the area
b. Drug solubility
c. Food in the stomach
d. Drug color
Rationale: Absorption depends on blood flow, solubility, and
the presence of food; drug color is irrelevant. Correct: a, b, c
,6. The time required for a drug’s plasma concentration to
decrease by half is called:
a. Peak time
b. Half-life
c. Bioavailability
d. Onset of action
Rationale: Half-life indicates how long it takes for drug
concentration to reduce by 50%. Correct: b
7. Which of the following are types of drug interactions?
a. Synergistic
b. Antagonistic
c. Additive
d. Reflexive
Rationale: Drugs can interact in ways that enhance, oppose, or
add to each other’s effects. Correct: a, b, c
8. Which of the following are signs of an allergic reaction to a
drug?
a. Rash
b. Fever
c. Anaphylaxis
d. Nausea
Rationale: Allergic reactions include skin rash, hives, and
potentially life-threatening anaphylaxis. Correct: a, c
, 9. The most accurate method of measuring a patient’s kidney
function for drug dosing is:
a. Urinalysis
b. Creatinine clearance
c. Blood pressure
d. Heart rate
Rationale: Creatinine clearance reflects kidney function and
guides dose adjustments. Correct: b
10. Which drugs require monitoring of serum levels to prevent
toxicity?
a. Digoxin
b. Gentamicin
c. Penicillin
d. Lithium
Rationale: Drugs with narrow therapeutic ranges need
monitoring to avoid toxicity. Correct: a, b, d
11. Which are considered high-alert medications?
a. Insulin
b. Heparin
c. Acetaminophen
d. Warfarin
