COMPREHENSIVE EXAM WITH
CORRECT ANSWERS
A 45-year-old man presents with sudden, severe right upper
quadrant pain after a fatty meal. Murphy’s sign positive.
Most likely diagnosis?
A. Acute cholecystitis
B. Acute cholangitis
C. Appendicitis
D. Peptic ulcer disease
Correct Answer: A
Rationale: Sudden RUQ pain with positive Murphy’s sign
after fatty meals is classic for acute cholecystitis.
A patient presents with fever, jaundice, and right upper
quadrant pain. Labs: elevated ALP, bilirubin, leukocytosis.
Most likely cause?
A. Ascending cholangitis
B. Hepatitis
C. Cholelithiasis
, D. Pancreatitis
Correct Answer: A
Rationale: Charcot triad (fever, jaundice, RUQ pain)
indicates acute cholangitis, often due to bile duct
obstruction.
A 65-year-old man presents with painless hematuria and a
bladder mass on imaging. Best next step?
A. Cystoscopy with biopsy
B. CT scan only
C. MRI only
D. Watchful waiting
Correct Answer: A
Rationale: Cystoscopy with biopsy is required to confirm
bladder cancer diagnosis.
A 70-year-old man presents with sudden, severe abdominal
pain, hypotension, and pulsatile abdominal mass.
Diagnosis?
A. Ruptured abdominal aortic aneurysm