Lehne’s Pharmacotherapeutics for
Advanced Practice Nurses and Physician
Assistants (2nd Edition Rosenthal Test
Bank)
b. Independent
Ch 1 Prescriptive Authority 2. Which factors increase the need for APRNs to have full
prescriptive authority?
a. More patients will have access to health care.
Ch 1 Prescriptive Authority 3. Which factors could be attributed to limited prescriptive
authority for APRNs? Select all that apply.
a. Inaccessibility of patient care
b. Higher health care costs
Ch 1 Prescriptive Authority 4. Which aspects support the APRN's provision for full prescriptive
authority? Select all that apply
a. Clinical education includes prescription of medications and disease processes.
c. National examinations provide validation of the APRN's ability to provide safe care.
d. Licensure ensures compliance with health care and safety standards.
Ch 1 Prescriptive Authority 5. Which aspects support the APRN's provision for full prescriptive
authority? Select all that apply.
a. Clinical education includes prescription of medications and disease processes.
c. National examinations provide validation of the APRN's ability to provide safe care.
d. Licensure ensures compliance with health care and safety standards.
Ch 1 Prescriptive Authority 6. A family nurse practitioner practicing in Maine is hired at a
practice across state lines in Virginia. Which aspect of practice may change for the APRN?
,a. The APRN will have less prescriptive authority in the new position.
Ch 2 Rational Drug Selection and Prescription Writing 7. How can collaboration with a
pharmacist improve positive outcomes for patients? Select all that apply.
b. Pharmacists have additional information on drug interactions.
c. The pharmacist can suggest adequate medication dosing.
d. Pharmacists have firsthand knowledge of the facility formulary.
Ch 2 Rational Drug Selection and Prescription Writing 8. A patient presents with delirium
tremens requiring Ativan administration. The provider of care is not in the facility. Which
action by the nurse is most appropriate?
a. Obtain a telephone order.
Ch 2 Rational Drug Selection and Prescription Writing 9. A patient with chronic pain calls the
provider's office to request a refill on their oxycontin. Which action is most appropriate?
b. Schedule an appointment with the patient.
Ch 2 Rational Drug Selection and Prescription Writing 10. A patient prescribed amoxicillin for
streptococcal pharyngitis reports new onset of a flat, itchy red rash on the chest and neck.
Which action is most important?
b. Discontinue the medication.
Ch 2 Rational Drug Selection and Prescription Writing 11. A patient taking three medications
for hypertension is diagnosed with COPD. Which action should be taken prior to prescribing
medications to treat COPD?
b. Obtain a complete medication history.
Ch 2 Rational Drug Selection and Prescription Writing 12. A patient with diabetes reports
losing their job and an inability to purchase required medications. Which action is most
appropriate?
c. Contact a different pharmacy.
Ch 2 Rational Drug Selection and Prescription Writing 13. A patient recently prescribed
hydrocodone calls to report they are unable to fill the prescription. Which factors could
contribute to the inability to fill the prescription? Select all that apply.
a. DEA number missing from prescription
b. Prescription sent via electronic messenger
d. Prescriber license number not included
,Ch 3 Promoting Positive Outcomes of Drug Therapy 14. A patient reports that a medication
prescribed for recurrent migraine headaches is not working. Which action should be taken
first?
a. Ask the patient about the number and frequency of tablets taken.
Ch 3 Promoting Positive Outcomes of Drug Therapy 15. A patient is prescribed metronidazole
for bacterial vaginosis. Which patient history finding would be most concerning?
c. Drinks two glasses of wine every night
Ch 3 Promoting Positive Outcomes of Drug Therapy 16. A patient is using a metered-dose
inhaler containing albuterol for asthma. The medication label instructs the patient to
administer "two puffs every 4 hours as needed for coughing or wheezing." The patient reports
feeling jittery sometimes when taking the medication, and she doesn't feel that the
medication is always effective. Which action is most appropriate?
c. Auscultating lung sounds and obtaining vital signs
Ch 3 Promoting Positive Outcomes of Drug Therapy 17. A patient newly diagnosed with
diabetes is to be discharged from the hospital. Which action should be taken first during
medication education?
a. Asking the patient to demonstrate how to measure and administer insulin
Ch 3 Promoting Positive Outcomes of Drug Therapy 18. The drug manual states that older
adult patients are at increased risk for hepatic side effects. Which action is most important
when prescribing this medication to an 80-year-old patient?
a. Obtain pretreatment laboratory work.
Ch 3 Promoting Positive Outcomes of Drug Therapy 19. A patient recently diagnosed with HIV
is prescribed several medications to treat the condition. Which factors could impact the
patient's adherence to the treatment regimen? Select all that apply.
a. The patient is uninsured
b. The patient works three part-time jobs
c. The medication regimen includes six different pills
e. Medication regimen requires medication be taken at regular 4-hour intervals.
Ch 3 Promoting Positive Outcomes of Drug Therapy 20. A patient diagnosed with bipolar
disorder is prescribed daily lithium. Which action is most important to determine if the
therapeutic level is maintained?
c. Ensure periodic laboratory testing is completed.
, Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 21. The nurse administers
naloxone [Narcan] to a patient who has received a toxic dose of morphine sulfate. The nurse
understands that the naloxone is effective because of which action?
c. Preventing activation of opioid receptors through antagonist actions
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 22. A patient is taking drug
X and receives a new prescription for drug Y, which is listed as an inducing agent. The nurse
caring for this patient understands that this patient may require doses of drug
c. higher; X
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 23. The nurse is preparing
to administer penicillin G intramuscularly to a child. The child's parents ask why the drug
cannot be given in an oral liquid form. What is the nurse's reply?
d. "This drug would be inactivated by enzymes in the stomach."
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 24. Which statement about
food and drug interactions is true?
d. Some foods can inhibit CYP isoenzymes and alter drug metabolism.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 25. A nurse is teaching a
patient about a drug that induces P-glycoprotein. The nurse will explain that this drug may
cause which effect on other drugs?
b. Decreased elimination through the kidneys
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 26. A patient claims to get
better effects with a tablet of Brand X of a drug than with a tablet of Brand Y of the same
drug. Both brands contain the same amount of the active ingredient. What does the nurse
know to be most likely?
c. Tablets can differ in composition and can have differing rates of disintegration and dissolution,
which can alter the drug's effects in the body.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 27. Two nurses are
discussing theories of drug-receptor interaction. Which statements are true regarding the
affinity of a drug and its receptor?
b. Affinity refers to the strength of the attraction between a drug and its receptor.
c. Drugs with high affinity are strongly attracted to their receptors.
e. The affinity of a drug for its receptors is reflected in its potency.
Advanced Practice Nurses and Physician
Assistants (2nd Edition Rosenthal Test
Bank)
b. Independent
Ch 1 Prescriptive Authority 2. Which factors increase the need for APRNs to have full
prescriptive authority?
a. More patients will have access to health care.
Ch 1 Prescriptive Authority 3. Which factors could be attributed to limited prescriptive
authority for APRNs? Select all that apply.
a. Inaccessibility of patient care
b. Higher health care costs
Ch 1 Prescriptive Authority 4. Which aspects support the APRN's provision for full prescriptive
authority? Select all that apply
a. Clinical education includes prescription of medications and disease processes.
c. National examinations provide validation of the APRN's ability to provide safe care.
d. Licensure ensures compliance with health care and safety standards.
Ch 1 Prescriptive Authority 5. Which aspects support the APRN's provision for full prescriptive
authority? Select all that apply.
a. Clinical education includes prescription of medications and disease processes.
c. National examinations provide validation of the APRN's ability to provide safe care.
d. Licensure ensures compliance with health care and safety standards.
Ch 1 Prescriptive Authority 6. A family nurse practitioner practicing in Maine is hired at a
practice across state lines in Virginia. Which aspect of practice may change for the APRN?
,a. The APRN will have less prescriptive authority in the new position.
Ch 2 Rational Drug Selection and Prescription Writing 7. How can collaboration with a
pharmacist improve positive outcomes for patients? Select all that apply.
b. Pharmacists have additional information on drug interactions.
c. The pharmacist can suggest adequate medication dosing.
d. Pharmacists have firsthand knowledge of the facility formulary.
Ch 2 Rational Drug Selection and Prescription Writing 8. A patient presents with delirium
tremens requiring Ativan administration. The provider of care is not in the facility. Which
action by the nurse is most appropriate?
a. Obtain a telephone order.
Ch 2 Rational Drug Selection and Prescription Writing 9. A patient with chronic pain calls the
provider's office to request a refill on their oxycontin. Which action is most appropriate?
b. Schedule an appointment with the patient.
Ch 2 Rational Drug Selection and Prescription Writing 10. A patient prescribed amoxicillin for
streptococcal pharyngitis reports new onset of a flat, itchy red rash on the chest and neck.
Which action is most important?
b. Discontinue the medication.
Ch 2 Rational Drug Selection and Prescription Writing 11. A patient taking three medications
for hypertension is diagnosed with COPD. Which action should be taken prior to prescribing
medications to treat COPD?
b. Obtain a complete medication history.
Ch 2 Rational Drug Selection and Prescription Writing 12. A patient with diabetes reports
losing their job and an inability to purchase required medications. Which action is most
appropriate?
c. Contact a different pharmacy.
Ch 2 Rational Drug Selection and Prescription Writing 13. A patient recently prescribed
hydrocodone calls to report they are unable to fill the prescription. Which factors could
contribute to the inability to fill the prescription? Select all that apply.
a. DEA number missing from prescription
b. Prescription sent via electronic messenger
d. Prescriber license number not included
,Ch 3 Promoting Positive Outcomes of Drug Therapy 14. A patient reports that a medication
prescribed for recurrent migraine headaches is not working. Which action should be taken
first?
a. Ask the patient about the number and frequency of tablets taken.
Ch 3 Promoting Positive Outcomes of Drug Therapy 15. A patient is prescribed metronidazole
for bacterial vaginosis. Which patient history finding would be most concerning?
c. Drinks two glasses of wine every night
Ch 3 Promoting Positive Outcomes of Drug Therapy 16. A patient is using a metered-dose
inhaler containing albuterol for asthma. The medication label instructs the patient to
administer "two puffs every 4 hours as needed for coughing or wheezing." The patient reports
feeling jittery sometimes when taking the medication, and she doesn't feel that the
medication is always effective. Which action is most appropriate?
c. Auscultating lung sounds and obtaining vital signs
Ch 3 Promoting Positive Outcomes of Drug Therapy 17. A patient newly diagnosed with
diabetes is to be discharged from the hospital. Which action should be taken first during
medication education?
a. Asking the patient to demonstrate how to measure and administer insulin
Ch 3 Promoting Positive Outcomes of Drug Therapy 18. The drug manual states that older
adult patients are at increased risk for hepatic side effects. Which action is most important
when prescribing this medication to an 80-year-old patient?
a. Obtain pretreatment laboratory work.
Ch 3 Promoting Positive Outcomes of Drug Therapy 19. A patient recently diagnosed with HIV
is prescribed several medications to treat the condition. Which factors could impact the
patient's adherence to the treatment regimen? Select all that apply.
a. The patient is uninsured
b. The patient works three part-time jobs
c. The medication regimen includes six different pills
e. Medication regimen requires medication be taken at regular 4-hour intervals.
Ch 3 Promoting Positive Outcomes of Drug Therapy 20. A patient diagnosed with bipolar
disorder is prescribed daily lithium. Which action is most important to determine if the
therapeutic level is maintained?
c. Ensure periodic laboratory testing is completed.
, Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 21. The nurse administers
naloxone [Narcan] to a patient who has received a toxic dose of morphine sulfate. The nurse
understands that the naloxone is effective because of which action?
c. Preventing activation of opioid receptors through antagonist actions
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 22. A patient is taking drug
X and receives a new prescription for drug Y, which is listed as an inducing agent. The nurse
caring for this patient understands that this patient may require doses of drug
c. higher; X
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 23. The nurse is preparing
to administer penicillin G intramuscularly to a child. The child's parents ask why the drug
cannot be given in an oral liquid form. What is the nurse's reply?
d. "This drug would be inactivated by enzymes in the stomach."
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 24. Which statement about
food and drug interactions is true?
d. Some foods can inhibit CYP isoenzymes and alter drug metabolism.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 25. A nurse is teaching a
patient about a drug that induces P-glycoprotein. The nurse will explain that this drug may
cause which effect on other drugs?
b. Decreased elimination through the kidneys
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 26. A patient claims to get
better effects with a tablet of Brand X of a drug than with a tablet of Brand Y of the same
drug. Both brands contain the same amount of the active ingredient. What does the nurse
know to be most likely?
c. Tablets can differ in composition and can have differing rates of disintegration and dissolution,
which can alter the drug's effects in the body.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 27. Two nurses are
discussing theories of drug-receptor interaction. Which statements are true regarding the
affinity of a drug and its receptor?
b. Affinity refers to the strength of the attraction between a drug and its receptor.
c. Drugs with high affinity are strongly attracted to their receptors.
e. The affinity of a drug for its receptors is reflected in its potency.
