Page 1 of 28
“UWORLD 1 QUESTIONS & ANSWERS EXAM
2026 ”LATEST EXAM 2026 – 2027 SOLVED
QUESTIONS & ANSWERS VERIFIED 100%
GRADED A+ (LATEST VERSION) WELL REVISED
100% GUARANTEE PASS
Uworld 1
1) A 32-year-old male is brought to the physician's office because of weakness
and tingling that started in his feet and is now at his knees. The weakness
started a week ago and is getting worse every day.
Physical examination shows strength of 2/5 in both legs and absent deep tendon
reflexes in his knees. His past medical history is insignificant except for a mild
respiratory infection two weeks ago. This patient's condition is most likely associated
with which of the following?
A) Endoneural inflammatory infiltration
B) Toxin penetration through blood-nerve barrier
C) Endoneurial arteriole hyalinization
D) Mutations of a muscle structural protein gene
E) Endomysial inflammatory infiltration
A) Endoneural inflammatory infiltration
- Guillain Barre syndrome
weakness which is getting worse every day*
*Guillain Barre* syndrome
*Guillain Barre* syndrome, you see?
, Page 2 of 28
EndoNeural inflammatory infiltration
What do you see in Guillain Barre Syndrome ?
EndoNeural inflammatory infiltration
2) A 23-year-old woman with a broken nose comes to the emergency
department accompanied by her boyfriend. With the boyfriend present, she
explains that she tripped and fell in the bathroom, hitting her face on the
countertop.
When asked privately if she feels unsafe with her boyfriend, the patient says, "No,
everything is fine. He just gets a little crazy now and then when he has too much to
drink."
When questioned further about how she sustained her broken nose, she says,
"He pushed me and I fell, but I'm sure it won't happen again." Which of the
following is the most appropriate response to the patient?
A) "Can you help me understand why you remain in the relationship?"
B) "Do you have a safe place to go in an emergency?"
C)"I am concerned that you are in denial about your abuse.
D) "I know this is difficult, but it is important that you tell me the extent of the
abuse.
E) "May I have permission to discuss these issues with your boyfriend?"
B) "Do you have a safe place to go in an emergency?"
3) A study is conducted to assess the effect of beta-blocker therapy in patients
with acute myocardial infarction (MI). The study found that 20 patients out of
90 who took a beta-blocker during the week prior to developing an MI had a
major arrhythmia event during hospitalization.
The study also determined that 30 patients out of 70 who did not take any beta-
blocker developed a major arrhythmia. What was the odds ratio of developing major
arrhythmia in patients who took beta-blockers compared to those who did not take
beta-blockers?
a) (20 x 30) / (70 x 40)
b) (20 x 40) / (70 x 30)
c) (20 x 70) / (30 x 40)
d) (20 x 50) / (70 x 110)
e) (20 x 90) / (30 x 70)
b) (20 x 40) / (70 x 30)
, Page 3 of 28
4) A healthy 32 year old man has been consuming a high-potassium diet rich
in bananas and avocados for the past 2 weeks. He is found to have a urine
potassium concentration that is higher than his plasma potassium
concentration.
In a normal individual with high dietary potassium intake, which of the following
describes the amount of potassium in the tubular fluid as it flows along the nephron
in comparison to filtered potassium load?
a)
Bowman's: 100%
PCT: 35%
TAL: 10%
Collecting duct: 110%
Potassium is Filtered and reabsorbed
But the Only place where potassium is excreted is Collecting
duct where Aldosterone acts.
so what are the values for Potassium as it travels along the Kidney?
Bowman's - 100%
PCT- 35%
TAL- 10%
Collecting duct- 110%
How does Potassium change as it flows through the kidney?
100-35-10-110
5) A 34 year old man comes to the emergency department complaining of
weakness, dizziness, and paresthesias involving his face and extremities. He
has never had symptoms like this before.
Two hours earlier, he ate fish at a new Japanese restaurant. Neurological
examination shows reduced muscle strength and decreased deep tendon reflexes.
Which of the following parts of the action potential curve is most likely impaired in
this patient?
a) A
b) B
c) C
d) D
e) E
“UWORLD 1 QUESTIONS & ANSWERS EXAM
2026 ”LATEST EXAM 2026 – 2027 SOLVED
QUESTIONS & ANSWERS VERIFIED 100%
GRADED A+ (LATEST VERSION) WELL REVISED
100% GUARANTEE PASS
Uworld 1
1) A 32-year-old male is brought to the physician's office because of weakness
and tingling that started in his feet and is now at his knees. The weakness
started a week ago and is getting worse every day.
Physical examination shows strength of 2/5 in both legs and absent deep tendon
reflexes in his knees. His past medical history is insignificant except for a mild
respiratory infection two weeks ago. This patient's condition is most likely associated
with which of the following?
A) Endoneural inflammatory infiltration
B) Toxin penetration through blood-nerve barrier
C) Endoneurial arteriole hyalinization
D) Mutations of a muscle structural protein gene
E) Endomysial inflammatory infiltration
A) Endoneural inflammatory infiltration
- Guillain Barre syndrome
weakness which is getting worse every day*
*Guillain Barre* syndrome
*Guillain Barre* syndrome, you see?
, Page 2 of 28
EndoNeural inflammatory infiltration
What do you see in Guillain Barre Syndrome ?
EndoNeural inflammatory infiltration
2) A 23-year-old woman with a broken nose comes to the emergency
department accompanied by her boyfriend. With the boyfriend present, she
explains that she tripped and fell in the bathroom, hitting her face on the
countertop.
When asked privately if she feels unsafe with her boyfriend, the patient says, "No,
everything is fine. He just gets a little crazy now and then when he has too much to
drink."
When questioned further about how she sustained her broken nose, she says,
"He pushed me and I fell, but I'm sure it won't happen again." Which of the
following is the most appropriate response to the patient?
A) "Can you help me understand why you remain in the relationship?"
B) "Do you have a safe place to go in an emergency?"
C)"I am concerned that you are in denial about your abuse.
D) "I know this is difficult, but it is important that you tell me the extent of the
abuse.
E) "May I have permission to discuss these issues with your boyfriend?"
B) "Do you have a safe place to go in an emergency?"
3) A study is conducted to assess the effect of beta-blocker therapy in patients
with acute myocardial infarction (MI). The study found that 20 patients out of
90 who took a beta-blocker during the week prior to developing an MI had a
major arrhythmia event during hospitalization.
The study also determined that 30 patients out of 70 who did not take any beta-
blocker developed a major arrhythmia. What was the odds ratio of developing major
arrhythmia in patients who took beta-blockers compared to those who did not take
beta-blockers?
a) (20 x 30) / (70 x 40)
b) (20 x 40) / (70 x 30)
c) (20 x 70) / (30 x 40)
d) (20 x 50) / (70 x 110)
e) (20 x 90) / (30 x 70)
b) (20 x 40) / (70 x 30)
, Page 3 of 28
4) A healthy 32 year old man has been consuming a high-potassium diet rich
in bananas and avocados for the past 2 weeks. He is found to have a urine
potassium concentration that is higher than his plasma potassium
concentration.
In a normal individual with high dietary potassium intake, which of the following
describes the amount of potassium in the tubular fluid as it flows along the nephron
in comparison to filtered potassium load?
a)
Bowman's: 100%
PCT: 35%
TAL: 10%
Collecting duct: 110%
Potassium is Filtered and reabsorbed
But the Only place where potassium is excreted is Collecting
duct where Aldosterone acts.
so what are the values for Potassium as it travels along the Kidney?
Bowman's - 100%
PCT- 35%
TAL- 10%
Collecting duct- 110%
How does Potassium change as it flows through the kidney?
100-35-10-110
5) A 34 year old man comes to the emergency department complaining of
weakness, dizziness, and paresthesias involving his face and extremities. He
has never had symptoms like this before.
Two hours earlier, he ate fish at a new Japanese restaurant. Neurological
examination shows reduced muscle strength and decreased deep tendon reflexes.
Which of the following parts of the action potential curve is most likely impaired in
this patient?
a) A
b) B
c) C
d) D
e) E
