NSC 830: ANTIBIOTICS EXAM QUESTIONS WITH COMPLETE SOLUTIONS

NSC 830: ANTIBIOTICS EXAM QUESTIONS WITH COMPLETE SOLUTIONS Why does a gram positive stain show up purple - answer-There is a thick peptidoglycogen layer that takes up crystal violet stain why does gram negative stain pink/red? - answer-takes up counterstain to appear that color how many layers does a gram negative bacteria have? - answer-3- thin peptidoglycogen layer sandwiched between an inner and outer cell membrane What color does atypical bacteria stain? - answer-no color Why doesn't atypical bacteria have a color stain? - answer-there is no peptidoglycogen layer Minimum inhibitory concentration (MIC) - answer-the smallest concentration of drug that visibly inhibits growth antibiotics that inhibits cell wall synthesis - answer-penicillin cephalosporins vancomycin fosfomycin antibiotic that inhibit bacterial protein synthesis - answer-tetracylines macrolides lincosamide mupiricinoxazolididone aminoglycoside MISC method of action antibiotic - answer-fluoroquinolones - DNA metronidazole sulfonamides - DNA nitrofurantion- DNA which abx are ONLY gram negative - answer-aminoglycosides metronidazole which abx are ONLY gram positive - answer-Vancomycin oxazolidinone which abx are gram -/+/atypical - answer-tetracylines macrolides sulfonamides are penicillins broad or narrow spectrum? - answer-both When to use broad spectrum PCN - answer-Acute sinusitis strep pharyngitis cellulitis acute otitis media uncomplicated UTI indication for 1st gen cephalosporins - answer-skin infection surgical prophylaxis CA- MRSAWhen to use 2nd gen cephalosporins - answer-otitis media acute sinusitis UTI Resp. tract infecton indication for 3rd gen cephalosporins - answer-otitis media (complicated/severe) CAP meningitis