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HESI A2 Anatomy & Physiology | 2026 Master Guide | 300+ Expert Verified Q&A | Hormones, Muscles, Organs, Reproduction

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This detailed and professionally structured study guide contains 300+ expertly verified questions and answers for the 2026 HESI A2 Anatomy and Physiology exam. Spanning 21 pages, this resource blends accurate definitions with critical exam concepts to help nursing and allied health students build confidence and deepen understanding of human body systems. Key topics covered across the guide include: Anatomical positions and body planes (e.g., anatomic position, medial, lateral, sagittal, transverse) Tissue types and histology (epithelial, connective, muscle, nerve) Cellular structure and function (nucleus, ribosomes, ATP, mitosis, meiosis, chromosomes) Integumentary system (epidermis layers, glands, keratin, melanin, thermoregulation) Skeletal system (bone types, osteoblasts, axial vs. appendicular, joints, bone marrow) Muscular system (muscle types, myofibrils, actin/myosin, muscle contraction, synergists) Nervous system (neurons, CNS/PNS, brain lobes, spinal cord, sensory vs. motor neurons) Endocrine system (pituitary gland, hypothalamus, steroid vs. nonsteroid hormones, tropic hormones) Cardiovascular and blood systems (atria, ventricles, valves, arteries/veins, blood components) Respiratory system (gas exchange, alveoli, diaphragm, medulla control center) Digestive system (alimentary canal, accessory organs, enzymes, absorption, chyme) Urinary system (kidneys, nephrons, ureters, glomerulus, urine formation) Reproductive system (FSH/LH, estrogen, testosterone, sperm path, corpus luteum, fertilization) The content reflects current standards for HESI testing and is ideal for learners needing: High-yield definitions Simplified explanations Flashcard-style reinforcement Recommended for: HESI A2 exam takers in 2026 Nursing, pre-nursing, and allied health students BSN, ADN, LPN, and medical prep applicants A&P learners seeking structured, full-body system review Keywords: HESI A2 2026, anatomy and physiology, tissue types, brain lobes, endocrine hormones, pituitary gland, skeletal system, bone types, nervous system, ATP, blood components, nephron, reproductive cycle, FSH, LH, testicular function, heart valves, lungs, muscular system, organ systems, verified answers

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HESI A2 Anatomy and Physiology


Anatomic Position - 🧠ANSWER ✔✔The body is erect, the feet are slightly

apart, the head is held high, and the palms of the hands are facing forward.


Superior - 🧠ANSWER ✔✔Above


Inferior - 🧠ANSWER ✔✔Below


Anterior - 🧠ANSWER ✔✔Facing forward


Posterior - 🧠ANSWER ✔✔Toward the back


Medial - 🧠ANSWER ✔✔Toward the midline


Lateral - 🧠ANSWER ✔✔Away from the midline; towards the side


Proximal - 🧠ANSWER ✔✔closer to point of attachment

,Distal - 🧠ANSWER ✔✔Farther away from point of attachment


Histology - 🧠ANSWER ✔✔Study of tissues


Tissue - 🧠ANSWER ✔✔Group of cells that act together to perform specific

functions


Epithelial cells - 🧠ANSWER ✔✔Cover, line, and protect the body and its

internal organs


Connective tissue - 🧠ANSWER ✔✔Framework of the body, providing

support and structure for the organs


Nerve Tissue - 🧠ANSWER ✔✔Composed of neurons


Muscle Tissue - 🧠ANSWER ✔✔Classified as voluntary muscle (skeletal

muscle) or involuntary muscle (smooth and cardiac muscle tissue); Have

the ability to contract or shorten


Cell - 🧠ANSWER ✔✔Basic unit of life and the building blocks of tissues and

organs


Nucleus - 🧠ANSWER ✔✔Contains DNA

, Ribosomes - 🧠ANSWER ✔✔Synthesis of proteins; proteins include the

enzymes that regulate all chemical reactions within the body


Mitosis - 🧠ANSWER ✔✔Necessary for growth and repair; in this process

DNA is duplicated and distributed evenly to two daughter cells


Meiosis - 🧠ANSWER ✔✔Cell division that takes place in the gonads

(ovaries and testes); chromosome number is reduced from 46 to 23 so

when the egg and the sperm unite in fertilization; the zygote will have

correct number of chromosomes


Skin - 🧠ANSWER ✔✔Largest organ in the body


Epidermis - 🧠ANSWER ✔✔Outermost protective layer made of dead,

keratinized epithelial cells


Dermis - 🧠ANSWER ✔✔Underlying layer of connective tissue with blood

vessels, nerve endings, hair follicles, glands, and the associated skin

structures; rests on subcutaneous tissue that connects the skin to the

superficial muscles


Layers of Epidermis (Outer to Inner) - 🧠ANSWER ✔✔1. Stratum corneum


2. Stratum Lucidum


3
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