NBME CBSE ACTUAL TEST QUESTIONS AND
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49 year old woman - coronary artery disease - BP 140/90 -
High Cholesterol, High LDL (190), High triglycerides (350)
- TX with atorvastatin and losartan. What are the effects
on HDL and Triglycerides? - Answers-HDL increased
Triglycerides Decreased
73 yeare old - diffuse weakness and tingling of her arms
and legs. Sensation and vibration and position is
decreased in all extremities. What vitamin deficiency? -
Answers-Vitamin B12 - (cyanocobalamin)
Tea and Toast - low B12 in diet
15 year old girl - 3 month history of acne - which is the
underlying cause of the patients acne? - Answers-
Stimulation of Sebaceous Glands by androgens
b. ACNE = Propionibacterium ACNE
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4 year old from Brazil - PE shows single 12x10cm lesion in
the right side of jaw with diffuse regular edges.
Photomicrographs of an incisional biopsy (looks like
Burkitts Lymphoma/ Starry night) - which of the processes
most likely to occur in the region indicated by the arrow? -
Answers-Apoptosis
b. Endemic Burkitt lymphoma can happen in Brazil as well
as Africa (jaw lesion, puffy face).
51 year old - lump on tongue - 1 pack smoking history for
30 years. 1.5 cm mass on apex of tongue. It is most
appropriate to evaluate which lymph nodes first for
evidence of metastasis? - Answers-Submental
15 year old boy - ER - 2 hour history of confusion and
agitation - fever, headache, stiff neck, and vomiting - since
returned from summer camp - patient is hallucinating -
lumbar puncture - shows cysts and trophozoites- most
likely pathogen? - Answers-a. Olfactory Nerve
Naegleria fowleri
17 year old - ED - 30 minutes after being found with a
blank stare. Physical exam shows rigidity. During exam he
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becomes hostile and assaults physician - Pt ingested
which drug? - Answers-PCP
Placebo controlled clinical trial - 5000 pts with essential
hypertension. 2500 patients receive new drug and 2500
patients receive placebo. If alpha is set at 0.01 instead of
0.05, which of the following is most likely result? -
Answers-Significant findings can be reported with greater
confidence
17 year old - gymnast - comes to hospital because of lack
of menstrual period for 6 months. BMI 15 Which is the
cause of the amenorrhea? - Answers-Hypogonadotropic
Hypogonadism
A male stillborn is delivered at 32 weeks -
Oligohydramnios - absence of a urethral opening. Which is
most likely finding? - Answers-Pulmonary Hypoplasia
A 6 day old - breast fed boy in ED - poor weight gain and
irritability since delivery - Physical exam shows jaundice
and hepatomegaly. The concentration of which of the
following metabolites is most likely increased? - Answers-
a. Galactose - 1 - phosphate
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b. Congenital intolerance to breast milk
A 25-year-old man - comes to ED - severe muscle pain,
diffuse, painful swelling of his neck, underarms, and groin
after camping in New Mexico Generalized scattered black
maculae. Examination of the right upper extremity shows
erythematous, solid, tender mass. Mass is draining blood
and necrotic material. The most effective antibiotic for
patient disorder will interfere with which of the following
processes? - Answers-a. Ribosomal Assembly
b. Yersenia Pestis
62 year old woman - osteoporosis - a bisphosphonate is
prescribed. The expected beneficial effect of the drug is
due to which of the following? - Answers-Decreased
Osteoclast Activity
Cohot Study of elderly women - relative risk ratio for hip
fractures among those who exercise regularly is 1.2 (95%
confidence interval of 1.1 to 1.8). Which of the following is
the conclusion about the effect of exercise on the risk of
hip fracture? - Answers-Statistically Significant Overall
Increase Risk