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ANCC FNP Actual Exam Version 1 (2026/2027) –
160 Real Exam Questions with 100% Correct
Answers | Grade A | NEW
Subject: ANCC Family Nurse Practitioner (FNP) Certification Exam
Preparation
Source: 2026/2027 ANCC FNP Actual Exam (Version 1, 160 Questions)
Format: Multiple-Choice Questions with Correct Answers and Rationales
1. A 72-year-old woman with a history of hypertension comes to
the emergency department with difficulty breathing. She has
experienced exertional shortness of breath over the last few weeks
and worsening symptoms at night when she lies flat.
Echocardiography demonstrates diffuse hypertrophy of the left
ventricle and an ejection fraction of 65%. In this patient population,
which of the following confers a mortality benefit?
A. Beta-blockers
B. Diuretics
C. Spironolactone
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D. ACE inhibitors
E. No agent has shown a mortality benefit in this population
Correct Answer: E. No agent has shown a mortality benefit in this
population
Rationale:
1. The clinical presentation (exertional dyspnea, orthopnea, preserved
ejection fraction of 65%, and left ventricular hypertrophy) is
consistent with heart failure with preserved ejection fraction
(HFpEF).
2. Large clinical trials have not demonstrated a consistent mortality
benefit for beta-blockers, diuretics, spironolactone, or ACE inhibitors
specifically in the HFpEF population.
3. Current management focuses on symptom control (e.g., diuretics for
volume overload) and treating comorbidities (e.g., hypertension,
atrial fibrillation), but no therapy has been proven to reduce
mortality in HFpEF.
2. When teaching smokers about starting nicotine gum to aid in
smoking cessation, tell them to:
A. Chew the gum like regular gum.
B. Chew until a peppery taste or tingling sensation is felt and then place in
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buccal mucosa.
C. Drink a cup of coffee before chewing the gum because it assists the
nicotine absorption.
D. Chew 1 piece every 4 hours for the first 6 weeks.
Correct Answer: B. Chew until a peppery taste or tingling
sensation is felt and then place in buccal mucosa
Rationale:
1. Nicotine gum is chewed slowly until a peppery taste or tingling is
felt, indicating nicotine release.
2. It is then "parked" between the cheek and gum to allow buccal
absorption, avoiding continuous chewing which can cause GI upset
and rapid nicotine release.
3. Chewing like regular gum or consuming caffeine does not enhance
absorption and may reduce efficacy.
3. Which human papillomavirus serotypes most commonly cause
cancer?
A. Serotypes 16 and 18.
B. Serotypes 6 and 11.
C. Serotypes 3 and 10.
D. Serotypes 27 and 29.
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Correct Answer: A. Serotypes 16 and 18
Rationale:
1. HPV types 16 and 18 are high-risk oncogenic strains responsible
for approximately 70% of cervical cancers and are linked to other
anogenital and oropharyngeal cancers.
2. Types 6 and 11 are low-risk, primarily causing genital warts and
recurrent respiratory papillomatosis.
3. Types 3, 10, 27, and 29 are associated with cutaneous warts, not
malignancy.
4. Thomas, age 35, uses a high-potency corticosteroid cream for a
dermatosis. He also currently has tinea corporis. You tell him the
following regarding the cream:
A. "You must use this for an extended period of time for it to be
effective."
B. "It will work better if you occlude the area."
C. "It may exacerbate your concurrent tinea corporis."
D. "Be sure to use it daily."
Correct Answer: C. "It may exacerbate your concurrent tinea
corporis."
Rationale:
ANCC FNP Actual Exam Version 1 (2026/2027) –
160 Real Exam Questions with 100% Correct
Answers | Grade A | NEW
Subject: ANCC Family Nurse Practitioner (FNP) Certification Exam
Preparation
Source: 2026/2027 ANCC FNP Actual Exam (Version 1, 160 Questions)
Format: Multiple-Choice Questions with Correct Answers and Rationales
1. A 72-year-old woman with a history of hypertension comes to
the emergency department with difficulty breathing. She has
experienced exertional shortness of breath over the last few weeks
and worsening symptoms at night when she lies flat.
Echocardiography demonstrates diffuse hypertrophy of the left
ventricle and an ejection fraction of 65%. In this patient population,
which of the following confers a mortality benefit?
A. Beta-blockers
B. Diuretics
C. Spironolactone
, 2|Page
D. ACE inhibitors
E. No agent has shown a mortality benefit in this population
Correct Answer: E. No agent has shown a mortality benefit in this
population
Rationale:
1. The clinical presentation (exertional dyspnea, orthopnea, preserved
ejection fraction of 65%, and left ventricular hypertrophy) is
consistent with heart failure with preserved ejection fraction
(HFpEF).
2. Large clinical trials have not demonstrated a consistent mortality
benefit for beta-blockers, diuretics, spironolactone, or ACE inhibitors
specifically in the HFpEF population.
3. Current management focuses on symptom control (e.g., diuretics for
volume overload) and treating comorbidities (e.g., hypertension,
atrial fibrillation), but no therapy has been proven to reduce
mortality in HFpEF.
2. When teaching smokers about starting nicotine gum to aid in
smoking cessation, tell them to:
A. Chew the gum like regular gum.
B. Chew until a peppery taste or tingling sensation is felt and then place in
, 3|Page
buccal mucosa.
C. Drink a cup of coffee before chewing the gum because it assists the
nicotine absorption.
D. Chew 1 piece every 4 hours for the first 6 weeks.
Correct Answer: B. Chew until a peppery taste or tingling
sensation is felt and then place in buccal mucosa
Rationale:
1. Nicotine gum is chewed slowly until a peppery taste or tingling is
felt, indicating nicotine release.
2. It is then "parked" between the cheek and gum to allow buccal
absorption, avoiding continuous chewing which can cause GI upset
and rapid nicotine release.
3. Chewing like regular gum or consuming caffeine does not enhance
absorption and may reduce efficacy.
3. Which human papillomavirus serotypes most commonly cause
cancer?
A. Serotypes 16 and 18.
B. Serotypes 6 and 11.
C. Serotypes 3 and 10.
D. Serotypes 27 and 29.
, 4|Page
Correct Answer: A. Serotypes 16 and 18
Rationale:
1. HPV types 16 and 18 are high-risk oncogenic strains responsible
for approximately 70% of cervical cancers and are linked to other
anogenital and oropharyngeal cancers.
2. Types 6 and 11 are low-risk, primarily causing genital warts and
recurrent respiratory papillomatosis.
3. Types 3, 10, 27, and 29 are associated with cutaneous warts, not
malignancy.
4. Thomas, age 35, uses a high-potency corticosteroid cream for a
dermatosis. He also currently has tinea corporis. You tell him the
following regarding the cream:
A. "You must use this for an extended period of time for it to be
effective."
B. "It will work better if you occlude the area."
C. "It may exacerbate your concurrent tinea corporis."
D. "Be sure to use it daily."
Correct Answer: C. "It may exacerbate your concurrent tinea
corporis."
Rationale:
