NURS 5334 - Antimicrobial Recall Quiz
Questions And Answers
/. Why do many medications lack pediatric dosing information in their drug labeling -
Answer-✅There is lack of evidence-based literature on the safe and effective use of
medications in children
/.Why are neonates at greater risk for toxicity with highly protein-bound drugs - Answer-
✅Protein binding is decreased in neonates increasing the amount of free drug available
/.At what age are adult levels of renal function achieved - Answer-✅12 months
/.What is the most accurate device for measuring a 2.5mL dose for a child - Answer-
✅An oral syringe
/.How do you help prevent medication errors - Answer-✅Write out the term daily
/.In pediatric patients gastric acidity does not reach adult values for - Answer-✅2 years
/.Nalidixic acid may cause _______ in children - Answer-✅cartilage erosion
/.Altered absorption of drugs in the elderly may result in _______ drug response -
Answer-✅Delayed
/.You have an elderly patient taking warfarin. You add another protein binding drug.
Which of the following statements is correct? - Answer-✅You will need to decrease
dose of warfarin
/.In elderly, proper index of renal function is _____ - Answer-✅Glomerular filtration rate
(GFR)
/.List that identifies drugs with high likelihood of cause adverse effects in elderly -
Answer-✅Beers list
/.Primary mechanism of antibacterial action of the penicillin's involve inhibition of -
Answer-✅Cell wall synthesis by binding and inactivating penicillin binding proteins
(PBPs)
, /.Which statement about vancomycin is accurate - Answer-✅Increases bacterial cell
wall permeability and inhibits RNA synthesis
/.The mechanism of action of the tetracyclines involves - Answer-✅Inhibiting protein
synthesis
/.Mechanism of action of aminoglycosides - Answer-✅Causes misreading of the code
on the mRNA template to inhibit protein synthesis
/.Which statement is accurate regarding the antibacterial action of gentamicin - Answer-
✅Gentamicin continues to exert antibacterial effects even after plasma level decrease
below detectable levels
/.If a patient was treated with the macrolide erythromycin, he/she should - Answer-
✅Temporarily stop simvastatin while taking erythromycin
/.24 year old woman returned from vacation abroad suffering from traveler's diarrhea,
and her problem has not responded to antidiarrheal drugs. A pathogenic gram-negative
bacillus is suspected. Which drug is most likely to be effective in the treatment of this
patient - Answer-✅Ciprofloxacin
/.Which is accurate about fluoroquinolones - Answer-✅Fluoroquinolones have different
therapeutic applications depending on the generation
/.Which adverse effect is MOST LIKELY to occur with sulfonamides - Answer-✅Skin
reactions
/.Which is true about ciprofloxacin - Answer-✅During treatment, tendonitis and even
tendon rupture may occur
/.Primary reason for the use of drug combinations in treatment of TB is to - Answer-
✅Delay or prevent emergence of resistance
/.Which is true about fluconazole - Answer-✅Primary route of excretion is renal
/.55 year old man has been on anticoagulant treatment for many years and is newly
diagnosed with TB. Which of the following antimycobacterial agents would MOST
LIKELY induce cytochrome P450 enzymes in the patient's liver thereby modifying the
effects of his anticoagulant treatment - Answer-✅Rifampin
/.Which drug is an antiviral that can be used to decrease shedding with genital herpes -
Answer-✅Valacyclovir
Questions And Answers
/. Why do many medications lack pediatric dosing information in their drug labeling -
Answer-✅There is lack of evidence-based literature on the safe and effective use of
medications in children
/.Why are neonates at greater risk for toxicity with highly protein-bound drugs - Answer-
✅Protein binding is decreased in neonates increasing the amount of free drug available
/.At what age are adult levels of renal function achieved - Answer-✅12 months
/.What is the most accurate device for measuring a 2.5mL dose for a child - Answer-
✅An oral syringe
/.How do you help prevent medication errors - Answer-✅Write out the term daily
/.In pediatric patients gastric acidity does not reach adult values for - Answer-✅2 years
/.Nalidixic acid may cause _______ in children - Answer-✅cartilage erosion
/.Altered absorption of drugs in the elderly may result in _______ drug response -
Answer-✅Delayed
/.You have an elderly patient taking warfarin. You add another protein binding drug.
Which of the following statements is correct? - Answer-✅You will need to decrease
dose of warfarin
/.In elderly, proper index of renal function is _____ - Answer-✅Glomerular filtration rate
(GFR)
/.List that identifies drugs with high likelihood of cause adverse effects in elderly -
Answer-✅Beers list
/.Primary mechanism of antibacterial action of the penicillin's involve inhibition of -
Answer-✅Cell wall synthesis by binding and inactivating penicillin binding proteins
(PBPs)
, /.Which statement about vancomycin is accurate - Answer-✅Increases bacterial cell
wall permeability and inhibits RNA synthesis
/.The mechanism of action of the tetracyclines involves - Answer-✅Inhibiting protein
synthesis
/.Mechanism of action of aminoglycosides - Answer-✅Causes misreading of the code
on the mRNA template to inhibit protein synthesis
/.Which statement is accurate regarding the antibacterial action of gentamicin - Answer-
✅Gentamicin continues to exert antibacterial effects even after plasma level decrease
below detectable levels
/.If a patient was treated with the macrolide erythromycin, he/she should - Answer-
✅Temporarily stop simvastatin while taking erythromycin
/.24 year old woman returned from vacation abroad suffering from traveler's diarrhea,
and her problem has not responded to antidiarrheal drugs. A pathogenic gram-negative
bacillus is suspected. Which drug is most likely to be effective in the treatment of this
patient - Answer-✅Ciprofloxacin
/.Which is accurate about fluoroquinolones - Answer-✅Fluoroquinolones have different
therapeutic applications depending on the generation
/.Which adverse effect is MOST LIKELY to occur with sulfonamides - Answer-✅Skin
reactions
/.Which is true about ciprofloxacin - Answer-✅During treatment, tendonitis and even
tendon rupture may occur
/.Primary reason for the use of drug combinations in treatment of TB is to - Answer-
✅Delay or prevent emergence of resistance
/.Which is true about fluconazole - Answer-✅Primary route of excretion is renal
/.55 year old man has been on anticoagulant treatment for many years and is newly
diagnosed with TB. Which of the following antimycobacterial agents would MOST
LIKELY induce cytochrome P450 enzymes in the patient's liver thereby modifying the
effects of his anticoagulant treatment - Answer-✅Rifampin
/.Which drug is an antiviral that can be used to decrease shedding with genital herpes -
Answer-✅Valacyclovir
